Toxicogenomic Approach to Risk Assessment of Welding Fumes

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Toxicogenomic Approach to Risk Assessment of Welding Fumes

Exposure to welding fumes is already known to produce respiratory effects, such as pulmonary function, pneumoconiosis, and lung cancer, along with certain non-respiratory results, such as manganism [1]. However, despite a large number of publications on the pathophysiological process of welding fume exposure-induced diseases to understand the disease process in vivo and in vitro, relatively few...

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Over the past several years, genomic technologies have evolved that enable the simultaneous analysis of the expression of hundreds to thousands of genes. This capability has completely changed the types of questions and the quality of information that can be queried by biomedical scientists. The functional status of a living cell can be characterized at the molecular level by its gene expressio...

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Concentration Evaluation and Health Risk Assessment of Welders' Exposure to Total Fumes and Manganese during Welding at Metal Industry

Introduction and purpose: Risk assessment of toxic or hazardous chemicals enables industrial hygienists to make appropriate decisions regarding management provisions in a healthy workplace. Exposure to total fumes and manganese during welding can have harmful effects on welders’ health. Therefore, the present study was conducted in the metal industry to evaluate the concentration and determine ...

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Bronchial reactions to exposure to welding fumes.

OBJECTIVES To study the airway response and its mechanism to welding fumes in six welders with respiratory symptoms. METHODS Methacholine and welding challenge tests were carried out. The concentration of welding fumes during the exposure test was measured. On two subjects who developed bronchoconstricition to welding challenge, additional tests were carried out including prick, patch, and in...

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Massive hemoptysis due to welding fumes

UNLABELLED Many pulmonary problems such as lung cancer, occupational asthma, and pneumoconiosis have been described due to welding in the literature until now. This is the first case report of alveolar hemorrhage due to welding fumes presented with massive hemoptysis. We report a rare case of massive hemopthisis associated with welder's lung, with a discussion based on a review of the literatur...

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ژورنال

عنوان ژورنال: Journal of Clinical Toxicology

سال: 2012

ISSN: 2161-0495

DOI: 10.4172/2161-0495.s5-004